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MLB Pitching Strikeouts Leaders — Records, Seasons, Career | StatVault
← All pitching strikeouts leaders
2026
MLB Season Leaders
Pitching Strikeouts
Top 25 of 561 qualifiers · regular season.
1
Jacob Misiorowski
P
· MIL
252
2
Gavin Williams
P
· CLE
248
3
Cam Schlittler
P
· NYY
239
4
Dylan Cease
P
· TOR
239
5
Cristopher Sánchez
P
· PHI
231
6
Jesús Luzardo
P
· PHI
221
7
Reid Detmers
P
· LAA
211
8
Logan Gilbert
P
· SEA
205
9
Taj Bradley
P
· MIN
205
10
Jacob deGrom
P
· TEX
201
11
Cade Cavalli
P
· WSH
200
12
Chris Sale
P
· ATL
200
13
Paul Skenes
P
· PIT
200
14
Nolan McLean
P
· NYM
194
15
Parker Messick
P
· CLE
193
16
Zack Wheeler
P
· PHI
193
17
Tarik Skubal
P
· LAD
186
18
Chase Burns
P
· CIN
185
19
Sean Burke
P
· CWS
185
20
Kevin Gausman
P
· TOR
184
21
Yoshinobu Yamamoto
P
· LAD
182
22
Aaron Nola
P
· PHI
177
23
Bryan Woo
P
· SEA
175
24
Drew Rasmussen
P
· TB
174
25
MacKenzie Gore
P
· TEX
174